一个方法框架允许在设计个性化干预时考虑个性化标记的识别
Alexandre Malmartel1, Philippe Ravaud2, Viet-Thi Tran2
1Université Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Center for Research in Epidemiology and StatisticS (CRESS), F-75004 Paris, France; Département de Médecine Générale, Université Paris Cité, F-75014 Paris, France.
Journal of clinical epidemiology
|June 13, 2023
概括
这项研究制定了一个框架,以优先考虑个性化戒烟干预措施的个人性标志物. 医生和患者确定了动机,信念和依赖等关键因素,这些因素对于定制治疗至关重要.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 行为科学 行为科学
- 临床干预开发 临床干预开发
背景情况:
- 个性化干预需要确定相关的个体因素 (人体标志物).
- 优先考虑这些标志物对于有效的戒烟计划至关重要.
- 现有研究和临床见解为选择潜在标记者提供了信息.
研究的目的:
- 创建一个方法框架,用于识别和优先考虑个人性标记.
- 应用这个框架来个性化戒烟干预措施.
主要方法:
- 从文献和专家采访中确定了36个潜在的人体标记.
- 医生 (n=795) 和前/现吸烟者 (n=793) 通过对对比来优先考虑标志物.
- 使用布拉德利·特里·卢斯模型分析数据.
主要成果:
- 医生优先考虑患者的动机,偏好和信仰 (例如,体重增加问题).
- 患者优先考虑他们的动机,吸烟行为和尼古丁依赖 (例如,Fagerström测试).
- 关于戒烟的动机的重要性,存在很大的共识.
结论:
- 提出了一个经过验证的框架,用于优先考虑戒烟的个人性标志物.
- 这一框架有助于开发更有效,个性化的干预措施.
- 了解患者和医生的观点是标记物选择的关键.
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