葡萄提取物对膜,下巴和骨骨的重塑的影响:一个范围的综述
Erdiarti Dyah Wahyuningtyas1, Ari Triwardhani1, I Gusti Aju Wahju Ardani1
1Department of Orthodontic, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
European journal of dentistry
|June 13, 2023
概括
葡萄种子提取物 (GSE) 显示出对骨健康有前景. 这次审查发现,动物体内的GSE补充剂促进骨形成,抑制再吸收,支持骨重塑和密度.
科学领域:
- * 药理学 药理学 药理学
- * 营养保健品 营养保健品
- * 骨生物学 骨生物学
背景情况:
- *草药在维持人类健康方面发挥着至关重要的作用.
- *葡萄种子提取物 (GSE) 是一种具有各种健康益处的显著草药补充剂.
- *新兴研究表明,GSE积极影响骨重塑过程.
研究的目的:
- * 在动物模型中对GSE对骨愈合和重塑的影响进行范围审查.
- * 分析GSE对大气管,大和骨骨的影响.
- *为人类骨健康提供GSE补充剂的未来研究和开发提供信息.
主要方法:
- *遵守系统审查和元分析 (PRISMA) 2020指南的首选报告项目.
- * 在主要数据库 (Scopus,PubMed,Science Direct,Web of Science,Embase) 进行全面的文献搜索和手动搜索,直到2022年12月.
- * 包含所有在体内研究,调查GSE补充对骨的影响.
主要成果:
- *在动物模型中,GSE补充剂被证明可以促进骨形成和抑制骨再吸收.
- * GSE有效地抑制了炎症,亡途径和骨质细胞形成,这对于骨重塑至关重要.
- *观察到的好处包括支持炎症,骨硬化,骨质疏松症和关节炎等疾病的骨重塑.
- * GSE增强了骨密度和矿物沉积,无论是状骨还是皮层骨结构.
结论:
- * GSE补充剂通过调节炎症和促进骨形成,对骨重塑产生积极影响.
- * GSE有效地防止骨再吸收并保持骨密度,有助于整体骨健康.
- *研究结果支持GSE作为治疗各种骨相关疾病的治疗剂的潜力.
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