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腹腔内通道整形与视镜辅助的透光轨道切除术在开角玻璃眼:一个随机对照试验

Peng Yin¹, Jiaying Li¹, Yan Shi¹

¹Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China.

The British journal of ophthalmology

|June 13, 2023

概括

与腹腔内运河整形术 (ABiC) 相比,视镜辅助的透光通道切除术 (GATT) 在开角绿眼病患者中显示出更好的眼内压力降低. 在手术后的12个月内,GATT还显示了有利的安全结果.

科学领域:

眼科医生眼科眼科
玻璃眼的手术玻璃眼的手术
最少侵入性玻璃眼外科手术

背景情况:

开角玻璃眼 (OAG) 是一种渐进的视神经病变,通常需要手术来控制眼内压力 (IOP).
腹腔管道整形术 (ABiC) 和阴视镜辅助透光通道切除术 (GATT) 是两种旨在改善水性幽默外流的微创性玻璃眼手术 (MIGS).
在ABiC和GATT之间比较的疗效和安全数据对于指导OAG管理中的外科选择至关重要.

研究的目的:

在被诊断患有开角玻璃眼 (OAG) 的患者中,比较腹腔内运河整形术 (ABiC) 与视镜辅助透光轨道切除术 (GATT) 的疗效和安全性.
为了评估眼内压力 (IOP) 降低和术后12个月的药物使用的差异.
评估完整的手术成功率,并确定与每个手术相关的任何不良事件.

主要方法:

一个随机临床试验涉及眼睛与OAG和没有先前的切口眼科手术.
参与者被随机分配到ABiC (38只眼睛) 或GATT (39只眼睛).
主要结局包括12个月内IOP和青光眼药物使用;次要结局是完全的手术成功.

主要成果:

在12个月后,与ABiC组相比,GATT组 (16.0±3.1 mm Hg) 的平均IOP明显低于ABiC组 (19.0±5.2 mm Hg;p=0.003).
虽然在统计学上不显著 (p=0.06),但GATT实现了更高的无药患者率 (77.8%) 与ABiC (57.2%) 相比.
整体手术成功的累积率在GATT (75%) 的情况下高于在12个月的ABiC (56%) (p=0.09).

结论:

与腹腔内运河整形术 (ABiC) 相比,视镜辅助的透光通道切除术 (GATT) 显示在降低眼内压力 (IOP) 方面具有统计学上显著的优势,对于开角玻璃眼病 (OAG) 患者来说.
该研究表明,GATT提供了有利的IOP减少和潜在的更好的手术成功率.
这两种手术都与特定的不良事件有关,在GATT小组中更频繁地观察到血和上溢液.

关键词:

眼光障碍眼光障碍眼光障碍眼光障碍治疗方法手术

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