口服补偿短肠患者是瘦的,可能营养不良,但很少有sarcopenic
Karen Bannert1, Cathleen Karbe1, Robert H Förster1
1Rostock University Medical Center, Department of Medicine II, Division of Gastroenterology and Endocrinology, Germany.
Clinical nutrition (Edinburgh, Scotland)
|June 13, 2023
概括
短肠综合征患者实现口腔自主性是较薄的,但通常保持正常的BMI. 虽然他们经常被诊断为营养不良,但尽管肌肉质量减少,他们很少患上肉症.
科学领域:
- 胃肠病学和肝病学 胃肠学和肝病学
- 营养科学 营养科学
- 老年病的医生 老年病的医生
背景情况:
- 短肠综合征 (SBS) 可以导致营养不良和代谢问题,因为肠道吸收能力降低.
- 肠道衰竭通常需要亲肠道营养 (PN),但有些SBS患者可以获得口腔自主.
- 短肠肠道功能不全 (SB/II) 患者的口服补偿需要评估他们的长期营养和功能状况.
研究的目的:
- 评估口服补偿SB/II患者的营养,肌肉和功能状况.
- 将SB/II患者与健康对照 (HC) 进行关键健康参数的比较.
主要方法:
- 对比28名口服补偿SB/II患者 (PN后平均46个月) 与56名年龄和性别匹配的HC患者.
- 评估的人类测量,身体组成 (生物电阻分析),手握强度,步行速度,血液参数,营养摄入量和身体活动.
- 根据GLIM和EWGSOP2标准诊断出营养不良和肉症.
主要成果:
- SB/II患者的BMI和人体指数低于HC,但是在正常体重范围内.
- 在39%的SB/II患者中诊断出营养不良;在15%的患者中诊断出肉症.
- 在SB/II患者中,肌肉质量减少 (39%) 和体力活动低 (37%),但很少出现功能障碍;在一些患者中观察到脱水症状.
结论:
- 口服补偿的SB/II患者通常较瘦,但体重指数正常,经常出现营养不良的诊断,可能受过的影响.
- 肌肉质量减少是常见的,但由于肌肉功能得到保护,肉症很少见.
- 长期,SB/II患者可能营养不良,但在停止PN后,通常会避免肉症.
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