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Updated: Jul 26, 2025

Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
06:52

Kinetic Screening of Nuclease Activity using Nucleic Acid Probes

Published on: November 1, 2019

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对阿尔戈纳特蛋白相关NADase激活在细菌免疫中的机制的结构洞察

Xiaoshen Wang1, Xuzichao Li1, Guimei Yu1

  • 1National key laboratory of blood science, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Haihe Laboratory of Cell Ecosystem, Tianjin Institute of Immunology, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.

Cell research
|June 13, 2023
PubMed
概括

与NADase酶连接的 Prokaryotic Argonaute (Ago) 蛋白质消耗了尼古丁胺胺氨基二核酸 (NAD+) 来对抗感染. 这项研究揭示了DNA结合如何激活这些关键的原生生物免疫系统.

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Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells09:04

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