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Updated: Jul 26, 2025

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform
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A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform

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RELA控制着贝塔细胞功能所必需的小岛特异性代谢基因网络

Nathan W Zammit1,2,3,4, Ying Ying Wong5, Stacey N Walters1,2

  • 1Transplantation Immunology Laboratory, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

Diabetologia
|June 13, 2023
PubMed
概括

转录因子RELA (p65) 对于β细胞中的正常葡萄糖代谢和胰岛素分泌至关重要,独立于其炎症作用. 这一发现影响了涉及NF-κB抑制剂的糖尿病治疗策略.

关键词:
贝塔细胞 贝塔细胞 贝塔细胞糖尿病 糖尿病 糖尿病增强器集线器的集线器葡萄糖皮质类药物是什么小小的岛屿 小小的岛屿代谢过程中的代谢.这就是NEMO.在 NF-κBB 中.在TNFAIP3中使用.p6565 这是一个很好的方法.

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