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饮食模式及其与多发性硬化症患者症状水平的关联:现实世界的数字研究
Lasse Skovgaard1, Philipp Trénel2, Katrine Westergaard3
1The Danish MS Society, Valby, Denmark. lsk@scleroseforeningen.dk.
Neurology and therapy
|June 13, 2023
概括
富含植物的饮食,特别是高蔬菜摄入量,可以减少多发性硬化症 (MS) 症状负担. 这项前性研究确定了丹麦的饮食模式及其与多发性硬化症症状的关联.
科学领域:
- 营养科学 营养科学
- 神经学 神经学
- 流行病学 流行病学
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经疾病.
- 饮食模式可能会影响MS症状的严重程度.
- 了解这些关联可以为支持性护理提供信息.
研究的目的:
- 研究多发性硬化症患者的长期食物摄入模式.
- 为了确定饮食习惯和报告的MS症状之间的关联.
- 探索饮食在控制症状负担中的作用.
主要方法:
- 未来的队列研究设计,在100天内与163名参与者进行100天的研究.
- 分层分类确定了饮食模式 (集群).
- 反向概率权衡分析了饮食和MS症状之间的关联.
主要成果:
- 三种饮食集群出现了:西方,植物丰富和多样化.
- 富含植物的饮食显著降低了9种多发性硬化症症状的症状负担 (19-90%的减少).
- 较高的蔬菜摄入量与显著的症状减少有关 (32-74%),特别是在疼痛,膀功能障碍,行走困难和疲劳方面.
结论:
- 饮食模式与多发性硬化症 (MS) 的症状负担有关.
- 增加蔬菜消费有望缓解多发性硬化症的症状.
- 饮食指南可以作为管理多发性硬化症症状严重性的宝贵工具.
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