在健康个体中甲状腺激素参考间隔 在中国兰州,健康个体中甲状腺激素参考间隔
Yan Lu1, Wen-Xia Zhang2, De-Hong Li1
1Department of Clinical Laboratory, Gansu Provincial Hospital, Lanzhou, China.
Endocrinology and metabolism (Seoul, Korea)
|June 14, 2023
概括
为中国兰州建立了新的甲状腺激素参考间隔. 这些新的性别特异值与制造商提供的范围不同,突出显示了局部甲状腺激素检测的必要性.
科学领域:
- 临床化学 临床化学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 目前在中国的甲状腺激素参考间隔 (RI) 取决于制造商.
- 区域差异和人口特异性因素需要地方RI建立.
研究的目的:
- 为了确定兰州人口的甲状腺激素RI.
- 将已确定的RI与制造商提供的值和以前的报告进行比较.
主要方法:
- 血清甲状腺激素度测量了来自兰州的3,123名健康个体.
- 使用了阿博特建筑师分析仪,并使用2.5和97.5百分比计算了95%的RI.
主要成果:
- 甲状腺激素水平与性别和年龄有显著的相关性.
- 确定的RI在性别之间存在差异,并且与制造商提供的值不一致.
- 在不同年龄组中,TSH,TT3,TT4和ATG的血清水平有所不同.
结论:
- 兰州健康人口的确定的甲状腺激素RI与制造商价值不同.
- 性别特定的参考间隔对于准确的甲状腺疾病诊断至关重要.
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