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空间转录学与单细胞RNA测序相结合,揭开了在亚托皮性皮肤炎中复杂的炎症细胞网络

Yasutaka Mitamura1, Matthias Reiger2,3,4, Juno Kim1

  • 1Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.

Allergy
|June 14, 2023
PubMed
概括

这项研究揭示了亚托皮炎 (AD) 皮肤病变中的细胞交叉声,确定了纤维细胞,巨细胞和树突细胞之间的相互作用. 血清TNC和CCL18水平升高与AD严重程度相关,为新的治疗提供了洞察力.

关键词:
亚托邦性皮肤炎的发生单细胞转录组学 单细胞转录组学空间转录学 空间转录学有针对性的蛋白质组学.

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