使用顺序器官衰竭评估 (SOFA) 评分和在有机酸盐中毒中血清乳酸盐水平进行结果预测
Govinda Balmuchu1, Manoj K Mohanty1, Manas R Sahu1
1Department of Forensic Medicine and Toxicology, AIIMS, Bhubaneswar, Odisha, India.
Journal of family medicine and primary care
|June 14, 2023
概括
序列器官衰竭评估 (SOFA) 评分有效预测有机中毒病例中的死亡率. 这种评分系统为评估有机中毒患者的结果提供了有价值的工具.
科学领域:
- 毒理学 毒理学 毒理学
- 临床医学 临床医学
- 关键的护理关键的护理
背景情况:
- 有机化合物是印度常见的农药,经常用于自杀中毒.
- 可访问性和广泛使用使得有机中毒成为严重的公共卫生问题.
研究的目的:
- 评估顺序器官衰竭评估 (SOFA) 评分在预测死亡率方面的有效性.
- 评估血清乳酸盐水平作为有机中毒死亡率预测指标的有用性.
主要方法:
- 一项前性观察性研究,涉及75名有机中毒患者.
- 使用的接收器操作特征 (ROC) 曲线分析和数据分析的后勤回归.
主要成果:
- SOFA得分显示,死亡率预测的曲线下的面积 (AUC) 为0.794.
- 血清乳酸水平显示AUC为0.659,表明与SOFA得分相比,预测值较低.
- 在幸存者和非幸存者之间观察到SOFA得分,乳酸,pH和住院时间的显著差异.
结论:
- SOFA评分是有机酸盐中毒死亡率的重要预测指标.
- SOFA评分可以可靠地用于预测有机中毒病例患者的结果.
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