髓寡腺细胞糖蛋白光学神经炎呈现与轨道顶部综合征
Farhana Nabila Sulaiman1,2, Nur Farhana Kamardin3, Mohamed Iliyas Sultan Abdul Kader4,5
1Department of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.
Cureus
|June 14, 2023
概括
这一案例突出显示了髓寡腺细胞糖蛋白抗体疾病 (MOGAD) 呈现为轨道顶部综合征. 早期免疫疗法治疗导致MOGAD患者的视力改善.
科学领域:
- 神经眼科神经眼科
- 免疫学 免疫学 免疫学
背景情况:
- 髓寡基细胞糖蛋白抗体疾病 (MOGAD) 是一种自身免疫性脱髓化疾病.
- 轨道顶部综合征 (OAS) 是一种罕见的疾病,其特征是眼和视力丧失.
研究的目的:
- 报告一个MOGAD病例,呈现出轨道顶部综合征.
- 为了突出MOGAD的各种临床表现.
主要方法:
- 一个36岁的男性患有急性视力丧失和眼的案例介绍.
- 临床检查,神经成像 (CT和MRI),以及针对抗转基因抗体的血清学测试.
- 用皮质类固醇治疗,血交换和静脉注射免疫球蛋白.
主要成果:
- 患者出现了单眼高度视觉缺陷,眼,右眼没有光感知.
- 神经成像显示光神经增强和轨道顶部拥挤.
- 阳性血清抗转基因抗体证实了诊断.
- 患者在免疫治疗后表现出缓慢的视觉改善.
结论:
- MOGAD可以呈现轨道顶部综合征,模仿其他导致眼和视力丧失的原因.
- 及时诊断和免疫治疗对于管理MOGAD至关重要.
- 这个案例扩大了MOGAD演讲的范围.
相关概念视频
Angle Closure Glaucoma: Treatment
578
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
578
Open Angle Glaucoma: Treatment
491
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
491
Glaucoma: Overview
633
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
633


