组合MIGS:比较化,内环光凝结和Kahook双刀片的添加效应
Blake Oberfeld1,2, Fatemeh Golsoorat Pahlaviani1, Nathan Hall1
1Glaucoma Service, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, MA, USA.
Clinical ophthalmology (Auckland, N.Z.)
|June 14, 2023
概括
结合法化,内循环光凝和Kahook双刀片 (PEcK) 显示出比其组件更大的眼内压力降低. 这种结合的MIGS方法可能会为玻璃眼患者提供更好的疗效.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 最少侵入性玻璃眼外科手术 (MIGS)
背景情况:
- 最少侵入性玻璃眼外科手术 (MIGS) 正在发展,联合手术 (cMIGS) 显示出比单一手术 (sMIGS) 更大的疗效潜力.
- 对cMIGS与其组成部分sMIGS的比较数据对于理解它们的相对益处至关重要.
研究的目的:
- 为了比较PEcK (Phacoemulsification,Endocyclophotocoagulation和Kahook双刀) 与其单个成分的疗效:Phaco/ECP和Phaco/KDB.
- 为了评估这些手术干预后的眼内压力 (IOP) 降低和药物负担.
主要方法:
- 在2016-2021年期间,对271名接受PEcK,Phaco/ECP或Phaco/KDB治疗的患者进行了1833次访问的回顾性分析.
- 使用一般估计方程 (GEE) 评估IOP和药物负担的主要结果,以及生存模型.
主要成果:
- 所有手术都显示了36个月内显著的IOP和药物减少 (p < 0.001).
- 与其他组相比,PEcK与其他组相比,随着时间的推移显示出明显不同的IOP减少模式 (p = 0.04),有利于PEcK.
- 对于IOP降低目标的程序时间或生存率没有发现显著差异.
结论:
- 与Phaco/ECP和Phaco/KDB相比,PEcK可以在轻度至中度青光瘤患者中提供优异的IOP降低.
- 未来对cMIGS的研究应该考虑对其单个MIGS组件进行比较分析.
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