肌肉间脂肪组织对代谢变化的重要作用 连接肥胖,衰老和运动:系统性审查
I Gusti Putu Suka Aryana1, Ivana Beatrice Paulus2, Sanjay Kalra3,4
1Geriatric Division, Department of Internal Medicine, Faculty of Medicine, Udayana University/Prof. I Goesti Ngoerah Gde Ngoerah Teaching Hospital, Denpasar, Bali, Indonesia.
TouchREVIEWS in endocrinology
|June 14, 2023
概括
肌肉间脂肪组织 (IMAT) 与代谢风险有关,特别是在老年人和肥胖个体中. 结合有氧和抵抗训练可以有效降低IMAT水平.
科学领域:
- 老年学是一门学科.
- 代谢健康 代谢健康
- 身体组成分析 身体成分分析
背景情况:
- 衰老导致肌肉和脂肪组织的变化,导致肉症.
- 肥胖症 (SO) 涉及过多的脂肪积累和瘦肉质量损失,影响代谢健康.
- 肌肉间脂肪组织 (IMAT) 与皮下脂肪不同,与代谢健康的关联不清楚.
研究的目的:
- 系统地审查肌肉间脂肪组织 (IMAT) 与代谢健康之间的联系.
- 综合目前关于IMAT在代谢风险因素中的作用的证据.
主要方法:
- 来自PubMed,Science Direct和Cochrane数据库的研究的系统审查.
- 数据提取和报告遵循了PRISMA指南.
- 包括两项临床试验和四项观察性研究,使用纽卡斯尔-太华尺度和CEBM检查清单进行评估.
主要成果:
- 肌肉间脂肪组织 (IMAT) 与代谢风险增加有关,特别是在老年人和肥胖患者中.
- 在患有腹部肥胖的人群中,内脏脂肪组织 (VAT) 在代谢风险中比IMAT发挥更重要的作用.
- 综合有氧和阻力训练表明,IMAT的减少最为显著.
结论:
- 肌肉间脂肪组织 (IMAT) 是代谢健康的一个重要因素,特别是在老龄化和肥胖的人群中.
- 虽然IMAT有助于代谢风险,但VAT可能是腹部肥胖的一个更重要的决定因素.
- 运动干预措施,特别是有氧和抵抗训练的联合训练,在管理IMAT水平方面是有效的.
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