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Updated: Jul 24, 2026

Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
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一种基于MVA的向量表达无细胞ISG15,增加IFN-I的产生,并改善HIV-1特异性CD8 T细胞免疫反应

Michela Falqui1, Beatriz Perdiguero2,3, Rocio Coloma1

  • 1Department of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid, Madrid, Spain.

Frontiers in cellular and infection microbiology
|June 14, 2023
PubMed
概括

干扰素刺激基因15 (ISG15) 作为免疫辅助剂,增强对HIV-1疫苗的反应. 通过MVA载体输送的ISG15 (ISG15AA) 的修饰形式比野生类型更有效地促进了HIV-1特定的CD8T细胞.

关键词:
艾滋病病毒 艾滋病病毒 艾滋病病毒国际货币基金组织 IFN IFN在ISG15中,我们可以看到ISG15.修改疫苗病毒 安卡拉一个辅助的辅助者.免疫力是一种免疫力.疫苗 疫苗 疫苗 疫苗

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