在年轻人发病的2型糖尿病中短期使用CGM与行为修改有关
Jacquelyn Manfredo1, Tyger Lin1, Radhika Gupta1
1Department of Pediatrics, Division of Endocrinology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Frontiers in endocrinology
|June 14, 2023
概括
持续血糖监测 (CGM) 的10天试验没有改善2型糖尿病 (T2D) 青少年的血糖控制. 然而,大多数参与者报告了积极的行为变化和长期使用CGM的愿望.
科学领域:
- 内分泌学 在内分泌学.
- 儿科 儿科 儿科
- 糖尿病管理 糖尿病管理
背景情况:
- 持续血糖监测 (CGM) 是为了改善1型糖尿病 (T1D) 和成人2型糖尿病 (T2D) 的血糖控制而建立的.
- 关于CGM在被诊断患有2型糖尿病 (T2D) 的年轻人中的疗效的研究有限.
研究的目的:
- 评估10天连续血糖监测 (CGM) 试验对2型糖尿病 (T2D) 青少年血糖控制和行为改变的影响.
主要方法:
- 一组41名患有T2D的青少年,接受胰岛素治疗并且没有CGM经验,接受了为期10天的CGM试验.
- 参与者获得了数据审查,行为调整和胰岛素定位的后续支持.
- 通过比较5天和10天的时间范围 (TIR) 和基线和3-6个月的HbA1c水平来评估血糖控制.
主要成果:
- 5天后的TIR平均值 (49%) 与10天后的TIR平均值 (51%) 相似,没有统计学上显著的差异 (p=0.62).
- 在基线 (10.3%) 和3-6个月的随访 (10.2%,p=0.89) 之间没有观察到HbA1c水平的显著变化.
- 尽管血糖水平没有显著改善,84%完成10天试验的参与者表示希望长期使用CGM,并报告了积极的行为变化.
结论:
- 短期,10天的CGM干预没有显著改善T2D青少年的血糖控制.
- 参与者报告了有益的行为改变和对继续使用CGM的强烈兴趣,这表明潜在的长期价值.
- 需要对延长CGM使用时间进行进一步的研究,以充分确定其在这个人群中的益处.
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