接种COVID-19疫苗后的皮肤不良事件
Sinee Weschawalit1, Padcha Pongcharoen1, Worapop Suthiwartnarueput2
1Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
Clinical, cosmetic and investigational dermatology
|June 14, 2023
概括
接种COVID-19疫苗的皮肤不良反应 (CARs) 不常见,影响1.2%的人. 潜在的疹和牛皮会增加患上这些轻微,暂时反应的风险.
科学领域:
- 皮肤病学 皮肤病学
- 疫苗学 疫苗学 疫苗学
- 流行病学 流行病学
背景情况:
- 在接种新冠病毒病 (COVID-19) 疫苗后出现的皮肤反应已被记录,但发病率和风险因素需要进一步调查.
- 关于不同人群中COVID-19疫苗接种后皮肤反应的具体特征和患病率的数据有限.
研究的目的:
- 为了确定泰国COVID-19疫苗接种后皮肤不良反应 (CARs) 的发生率.
- 根据疫苗类型和剂量来描述CARs的临床表现.
- 确定与CARs发展相关的独立风险因素.
主要方法:
- 一项前性观察性研究涉及7505名接受COVID-19疫苗接种的成年参与者.
- 皮肤学评估,包括必要时皮肤活检,以诊断皮肤反应.
- 使用描述性统计和后勤回归来评估风险因素的统计分析.
主要成果:
- 与疫苗相关的CAR总发病率为1.2% (92/7505),大多数反应发生在接种疫苗后7天内.
- 疹,注射部位反应和局部反应延迟是最常见的CAR (64%).
- 潜在的疹 (OR 15.63) 和牛皮 (OR 5.36) 被确定为发展CAR的独立风险因素.
结论:
- 接种COVID-19疫苗的皮肤不良反应是罕见的,通常是轻微的和短暂的.
- 患有先前存在的疹或牛皮的人在接种疫苗后面临患有CARs的风险更高.
- 这些发现有助于了解疫苗的安全性概况和管理潜在的皮肤反应.
相关概念视频
Skin Diseases and Disorders
3.9K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.9K
Allergic Reactions
27.9K
Overview
27.9K
Allergic Drug Reactions
898
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
898
Skin Cancer
4.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K
Vaccinations
44.8K
Overview
44.8K
Changes in Skin Color: Clinical Perspectives
2.0K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.0K


