宽容性和竞争在内和之间神经毛虫crassa syncytia
Alexander P Mela1, N Louise Glass1,2
1The Plant and Microbial Biology Department, University of California Berkeley, Berkeley, CA 94720, USA.
Genetics
|June 14, 2023
概括
丝状真菌使用syncytia进行协调生长. 这项研究揭示了syncytia耐受多种核类型,但不合作的细胞积极竞争资源,影响真菌进化.
科学领域:
- 菌类学 菌类学是指菌类学.
- 细胞生物学 细胞生物学
- 遗传学 是一个遗传学.
背景情况:
- 多核结合体在线状真菌中很常见,促进了协调的生长,繁殖和环境反应.
- 调节同胞细胞核和细胞质分布的精确机制在很大程度上仍未被探索.
研究的目的:
- 为了研究不同核种群在 *Neurospora crassa* syncytia 中的相对适应性.
- 了解如何syncytia管理核多样性,以及对真菌适应和进化的影响.
主要方法:
- 利用流细胞计与差异光标记的核组织蛋白来分析 *Neurospora crassa* 中的核种群.
- 评估了各种突变体的配对中同细胞体和异细胞体无性子体的分布,包括细胞融合或异细胞体不相容性有缺陷的突变体.
主要成果:
- 在同细胞体和异细胞体的无性子中都发现了突变核,这表明了维持突变的"投注对冲"策略.
- 阻断细胞融合或异质细胞不兼容的菌株的配对表现出"赢家占据全部"的结果,其中一种基因型主导无性子生产.
结论:
- 同胞性真菌细胞对广泛的核功能表现出耐受性.
- 不合作的真菌细胞或殖民地积极争夺资源,突出了syncytia在资源管理和真菌进化中的重要性.
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