低度乳腺状癌:一个罕见的病例呈现
Andleeb Abrari1, Durre Shehwar2, Kafil Akhtar2
1Department of Histopathology, The Rotherham NHS Foundation Trust, Rotherham, United Kingdom.
Journal of cancer research and therapeutics
|June 14, 2023
概括
低度腺性瘤是一种罕见的乳腺癌亚型,表现出惰的行为和良好的预后,尽管是三重阴性. 完整的手术切除对于防止这种不常见的恶性瘤复发至关重要.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 乳腺癌研究研究 乳腺癌研究
背景情况:
- 低度腺性瘤是一种罕见的转移性乳腺癌变体.
- 它表现出惰的行为和有利的预后,与积极的转移性癌瘤形成鲜明对比.
- 三重阴性状态很常见,但复发与不完全切除有关.
研究的目的:
- 为了呈现一种低度乳腺状癌的病例.
- 为了突出诊断挑战,由于平淡的细胞学特征模仿良性病变.
- 强调彻底切除对有利结果的重要性.
主要方法:
- 一个55岁的绝经后女性患有乳腺块的案例报告.
- 诊断工作包括乳腺扫描 (BIRADS 4C) 和核心针活检.
- 免疫组织化学证实了三重阴性状态和肌皮细胞标记物的阳性.
主要成果:
- 乳房扫描显示了一个具有建筑扭曲的高密度质量.
- 活检显示,在一个纤维肌状细胞层中,随机发生的腺体和状细胞.
- 免疫组织化学证实了三重阴性状态 (ER,PR,HER2阴性) 和CK 5/6,CK7,calponin和CD10的阳性.
结论:
- 低度腺性瘤可以被误认为是良性乳腺病变.
- 清晰边缘的完整的外科切除对于防止复发至关重要.
- 这种罕见的乳腺癌变体,尽管是三阴性,但在适当治疗的情况下预后良好.
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