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Updated: Jul 26, 2025

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
11:44

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

Published on: January 24, 2016

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SARS-CoV-2 NSP13与宿主IRF3相互作用,阻断抗病毒免疫反应

Kuan Feng1,2, Hui-Jiao Zhang2,3, Yuan-Qin Min2,4

  • 1Department of Pediatric Emergency, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.

Journal of medical virology
|June 14, 2023
PubMed
概括

严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) NSP13蛋白质通过直接准IRF3转录因子来阻止干扰素反应. 这种相互作用抑制了抗病毒基因表达,有助于病毒免疫逃避.

关键词:
在 IRF3 中,IRF3 包含了 IRF3 和 IRF3.在NSP13中,您可以使用NSP13.这就是SARS-CoV-2病毒.抗病毒天生的免疫力.免疫逃避 免疫逃避干扰的诱导作用是干扰的诱导作用.病毒与宿主之间的相互作用

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