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台湾患有心力衰竭和减少喷射分数的患者缺铁
Hsiao-Ping Sung1,2, Chien-Yi Hsu3,4,5, Ying-Hsiang Lee6,7
1Heart Center, Cheng Hsin General Hospital, Taipei, Taiwan, ROC.
Journal of the Chinese Medical Association : JCMA
|June 14, 2023
概括
缺铁 (ID) 在心力衰竭中常见,患者的射出分数减少 (HFrEF). 这一条件独立地预测了较差的结果,强调了在HFrEF管理中需要进行铁形状测试的必要性.
科学领域:
- 心脏病学 心脏病学
- 内部医学 内部医学
- 营养科学 营养科学
背景情况:
- 铁缺乏症 (ID) 是心力衰竭中常见的并发症,心力衰竭的降低射出分数 (HFrEF).
- ID与患者的治疗结果更差有关,不论是贫血.
- 本研究调查了台湾HFrEF患者中ID的患病率和预后影响.
研究的目的:
- 为了确定铁缺乏症在台湾HFrEF患者中的患病率.
- 评估该患者群体中缺铁的预后意义.
- 评估ID和不良心血管结果之间的关联.
主要方法:
- 来自两个不同的多中心队列的HFrEF患者的分析.
- 利用多变量考克斯回归来分析与ID相关的风险.
- 调整以考虑分析中的不同死亡风险.
主要成果:
- 在3612名HFrEF患者中,有18.4%的人有铁样本;其中43.6%的人患有ID.
- ID患者对所有原因死亡率 (HR 1.33),心血管死亡率 (HR 1.54) 和HF住院 (HR 1.57) 的风险更高.
- 腹腔铁疗法可能会减少每100个患者年中的13.7个HF住院和心血管死亡.
结论:
- 在台湾的HFrEF队列中,不到20%的铁样质被评估.
- 在43.6%的受试患者中,发现缺铁症.
- 在台湾的HFrEF患者中,ID独立地与预后不佳有关.
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