对过敏性鼻炎的诊断和实际治疗的最新情况
Chiara Trincianti1, Maria Angela Tosca1, Giorgio Ciprandi2
1Allergy Center, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Expert review of clinical pharmacology
|June 14, 2023
概括
过敏性鼻炎 (AR) 管理涉及各种治疗,包括过敏原特异性免疫疗法 (AIT) 作为唯一的因果疗法. 新兴战略重点是新配方和组合,以改善过敏性鼻炎护理.
科学领域:
- 过敏学 过敏学
- 免疫学 免疫学 免疫学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 过敏性鼻炎 (AR) 是一种普遍的疾病,通常与其他过敏性疾病同时发生.
- 诊断依赖于患者病史,敏感化证据 (例如,过敏原特异性IgE) 和分子诊断.
- 目前的治疗方法包括患者教育,非药物方法,药物和过敏原特异性免疫疗法 (AIT).
研究的目的:
- 审查当前和新的过敏性鼻炎管理策略.
- 突出AIT作为AR唯一因果治疗的作用.
- 讨论新兴的治疗方法,包括用于严重喘并发症的生物药物.
主要方法:
- 对当前和新出现的过敏性鼻炎管理的文献综述.
- 对药物和非药物治疗选择的分析.
- 对过敏原特异性免疫疗法 (AIT) 和生物制剂的评估.
主要成果:
- 过敏特异性免疫疗法 (AIT) 仍然是过敏性鼻炎的唯一因果治疗方法.
- 药理治疗包括鼻内/口服抗胰岛素和鼻腔皮质类固醇.
- 新兴的策略包括固定的鼻内抗胺-皮质类固醇组合,益生菌和新的AIT配方.
结论:
- 有效的过敏性鼻炎管理需要全面的方法.
- 过敏原特异性免疫疗法 (AIT) 对于因果治疗至关重要.
- 未来的方向包括探索新的药物组合,天然物质和先进的AIT输送系统.
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