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Updated: Aug 7, 2026

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates
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阿格马丁-IRF2BP2相互作用通过增加IRF2-KLF4信号传递来诱导微质的M2表型

Jiwon Kim1,2, A Young Sim1,2, Sumit Barua1

  • 1Department of Anatomy, Yonsei University College of Medicine, 50-1, Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]
|June 14, 2023
PubMed
概括

阿格马丁 (Agm) 结合了IRF2BP2,释放了IRF2以激活KLF4. 这种机制增强了微质的抗炎反应,为中枢神经系统受伤提供神经保护.

关键词:
亚格马提因 (Agmatine) 是一种亚格马提因.在 IRF2 中, IRF2 是 IRF2 的一个类型.在 IRF2BP2BP2 中,您可以使用 IRF2BP2在KLF4KLF4微质细胞中的微质细胞神经炎症是一种神经炎症.

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Author Spotlight: Induced Microglia-Like Cell Technology to Shed Light on the Role of Microglial Dysfunction in Neuropsychiatric Disorders06:12

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