癌症患者PICC-RVT的临床因素:一个元分析
Shengmiao Ma1, Chen Shen1, Qiuyue Li1
1School of Nursing, Chinese Academy of Medical Sciences & Peking Union Medical College, NO.9 Dong Dan San Tiao, Beijing, 100730, China.
概括
癌症患者有化疗史,特定瘤类型,晚期,转移和某些化疗药物面临较高的风险外围插入中央导管相关静脉血栓形成 (PICC-RVT). 对这些高风险个体来说,密切监测至关重要.
科学领域:
- 在瘤学瘤学.
- 血管医学 血管医学
- 医疗信息学 医疗信息学
背景情况:
- 周围插入的中央导管 (PICC) 对于癌症患者的治疗至关重要.
- 导管相关静脉血栓塞 (CRVT) 是一个显著的并发症.
- 在癌症患者中对PICC相关静脉血栓形成 (PICC-RVT) 的临床因素进行了有限的系统评估.
研究的目的:
- 系统地评估与癌症患者PICC-RVT相关的临床因素.
- 确定PICC-RVT的风险因素,包括治疗,瘤阶段,转移和化疗药物.
- 为PICC-RVT提供临床预防和减少策略的证据.
主要方法:
- 一个系统的审查和相关研究的元分析.
- 在主要数据库 (PubMed,Embase,Web of Science,CNKI,WanFang,CMB) 进行文献搜索,直到2022年7月.
- 使用RevMan 5.4.1进行的定量分析,用于聚合结果.
主要成果:
- 包括19篇涉及19824名患者的文章.
- 分析确定了化疗史,瘤类型,瘤阶段和转移作为PICC-RVT的风险因素.
- 特定的化疗药物 (甲,埃托波,类药物,塔克森) 与增加PICC-RVT风险有关.
结论:
- 患有已确定的风险因素的患者需要对PICC-RVT进行更密切的监测.
- 化疗史,瘤特征和特定药物使用是PICC-RVT预防的关键考虑因素.
- 在本分析中,放射治疗没有与PICC-RVT形成有关.
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