前列腺动脉栓塞用于治疗与良性前列腺扩大相关的下尿路症状
Patrick Curtin1, Christopher Chang2, Andre Uflacker3
1Department of Urology, Medical University of South Carolina, Charleston, SC, USA. curtin@musc.edu.
Current urology reports
|June 14, 2023
概括
前列腺动脉栓塞 (PAE) 为良性前列腺缩提供类似的症状缓解,以通过尿道切除前列腺 (TURP). PAE显示出有利的安全概况,住院时间较短,不良事件较少.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 干预性放射学 干预性放射学
- 最少侵入性手术的方法
背景情况:
- 良性前列腺缩 (BPH) 是一种常见的疾病,导致下泌尿道症状 (LUTS).
- 通过尿道切除前列腺 (TURP) 是BPH的黄金标准治疗方法.
- 前列腺动脉栓塞 (PAE) 是BPH管理的一个新兴的微创替代方案.
研究的目的:
- 审查目前的证据,比较PAE与TURRP用于BPH治疗.
- 评估PAE在管理与BPH相关的LUTS的疗效和安全性.
- 评估患者报告的结果和PAE后的客观测量.
主要方法:
- 对元分析和比较研究的系统审查.
- 分析患者驱动的指标 (例如,IPSS,IPSS-QoL) 和客观参数 (例如,Qmax,PVR).
- 在PAE和TURP之间对不良事件概况和住院时间的比较.
主要成果:
- 在治疗术后12个月内,PAE在改善患者报告的LUTS方面显示出与TURP相似的疗效.
- 客观测量 (Qmax,PVR) 也显示了PAE和TURP之间的类似结果.
- 与TURP相比,PAE与更短的住院时间和较低的不良事件发生率有关.
结论:
- 在BPH患者中,PAE是管理LUTS的安全有效替代方案,提供了有利的安全性.
- 虽然长期耐用性数据仍在出现,但PAE为寻求避免穿尿道手术的患者提供了有价值的选择.
- 泌尿科医生应建议患者使用PAE作为可行的替代方案,强调其益处和潜在的局限性.
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