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Updated: Jul 26, 2025

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
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Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation

Published on: November 26, 2018

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在慢性淋巴细胞白血病患者中,B细胞受体路径突变很少发生,这些患者在持续的易布鲁替尼治疗中

Jennifer A Woyach1, Paolo Ghia2, John C Byrd3

  • 1The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.

Clinical cancer research : an official journal of the American Association for Cancer Research
|June 14, 2023
PubMed
概括

在没有疾病进展的慢性淋巴细胞白血病 (CLL) 患者中,布鲁顿的氨酸激酶 (BTK) 和脂酶C-γ2 (PLCG2) 基因中获得的突变很少见. 然而,这些突变在接受伊布鲁替尼治疗的复发性/耐药性CLL患者中更为频繁.

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