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Updated: Jul 26, 2025

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无意义介导的RNA衰变导致在DUX4表达时截断的RNA结合蛋白的产生

Amy E Campbell1, Michael C Dyle1, Roberto Albanese2

  • 1Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.

Cell reports
|June 14, 2023
PubMed
概括

无理性介导的RNA衰变 (NMD) 的丧失导致了广泛的截断蛋白质生产. 这包括有毒的SRSF3变种,影响FSHD和其他遗传疾病.

关键词:
科普:分子生物学 分子生物学DUX4X4 的使用情况这是FSHD的FSHD.没有NMD的手机.在RNA衰变过程中,RNA衰变.消极症是一种消极症,消极症是消极症.肌肉 肌肉 肌肉 肌肉质量控制质量控制质量控制拼接 拼接 拼接 拼接翻译翻译翻译翻译翻译翻译

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