Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Membrane Fluidity01:26

Membrane Fluidity

11.3K
Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is...
11.3K
Fluid Mosaic Model01:19

Fluid Mosaic Model

12.0K
Scientists identified the plasma membrane in the 1890s and its principal chemical components (lipids and proteins) by 1915. The model for plasma membrane structure, proposed in 1935 by Hugh Davson and James Danielli, was the first model to be widely accepted in the scientific community. The model was based on the plasma membrane's "railroad track" appearance in early electron micrographs. Davson and Danielli theorized that the plasma membrane's structure resembled a sandwich...
12.0K
What are Lipids?01:31

What are Lipids?

7.6K
Lipids function as structural components of cellular membranes, in addition to acting as energy reservoirs and signaling molecules. They are thus crucial to all living organisms.  The three biologically important classes of lipids are triglycerides, phospholipids, and steroids.
Non-Polar and Hydrophobic Characteristics of Lipids
Lipids are a structurally and functionally diverse group of hydrocarbons—compounds consisting of carbon and hydrogen atoms. The carbon-carbon and...
7.6K
Asymmetric Lipid Bilayer01:35

Asymmetric Lipid Bilayer

7.3K
Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...
7.3K
Comparing Intermolecular Forces: Melting Point, Boiling Point, and Miscibility02:34

Comparing Intermolecular Forces: Melting Point, Boiling Point, and Miscibility

44.6K
Intermolecular forces are attractive forces that exist between molecules. They dictate several bulk properties, such as melting points, boiling points, and solubilities (miscibilities) of substances. Molar mass, molecular shape, and polarity affect the strength of different intermolecular forces, which influence the magnitude of physical properties across a family of molecules.
Temporary attractive forces like dispersion are present in all molecules, whether they are polar or nonpolar. They...
44.6K
Intermolecular Forces and Physical Properties02:56

Intermolecular Forces and Physical Properties

20.9K
20.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Chain-length-dependent partitioning of 1-alkanols in raft-like lipid membranes.

The Journal of chemical physics·2026
Same author

Oxysterol Induced Fluid-Fluid Phase Separation in Saturated Phosphatidylcholine Membranes: Influence of Lipid Chain Length.

The Journal of membrane biology·2026
Same author

Influence of Alcohols on the Bending Rigidity and the Thickness of Phospholipid Membranes: The Role of Chain Length Mismatch.

The journal of physical chemistry. B·2025
Same author

Clustering of lipids driven by integrin.

Soft matter·2023
Same author

Molecular Mechanism of Hydrotropic Properties of GTP and ATP.

The journal of physical chemistry. B·2022
Same author

Experimental and computational studies of cellulases as bioethanol enzymes.

Bioengineered·2022

相关实验视频

Updated: Jul 26, 2025

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches
07:31

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

2.3K

闭环流体-流体不混合性在二元脂质-胆固醇膜中.

Md Arif Kamal1,2,3, Anirban Polley1, P K Shabeeb1

  • 1Soft Condensed Matter Group, Raman Research Institute, Bengaluru 560080, India.

Proceedings of the National Academy of Sciences of the United States of America
|June 14, 2023
PubMed
概括

两个双重的脂质-胆固醇膜系统显示出不寻常的流体-流体共存. 膜中取决于温度的氧乙醇导向驱动了这种独特的相位行为,创造了不混合性差距.

关键词:
封闭循环的不混合性.流体流体的共存.脂质胆固醇的膜.

更多相关视频

Biomembrane Fabrication by the Solvent-assisted Lipid Bilayer SALB Method
09:38

Biomembrane Fabrication by the Solvent-assisted Lipid Bilayer SALB Method

Published on: December 1, 2015

15.0K
Fluorescence Recovery after Merging a Droplet to Measure the Two-dimensional Diffusion of a Phospholipid Monolayer
07:54

Fluorescence Recovery after Merging a Droplet to Measure the Two-dimensional Diffusion of a Phospholipid Monolayer

Published on: October 15, 2015

8.1K

相关实验视频

Last Updated: Jul 26, 2025

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches
07:31

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

2.3K
Biomembrane Fabrication by the Solvent-assisted Lipid Bilayer SALB Method
09:38

Biomembrane Fabrication by the Solvent-assisted Lipid Bilayer SALB Method

Published on: December 1, 2015

15.0K
Fluorescence Recovery after Merging a Droplet to Measure the Two-dimensional Diffusion of a Phospholipid Monolayer
07:54

Fluorescence Recovery after Merging a Droplet to Measure the Two-dimensional Diffusion of a Phospholipid Monolayer

Published on: October 15, 2015

8.1K

科学领域:

  • 膜生物物理学 膜生物物理学
  • 脂质 - 胆固醇相互作用
  • 生物膜的相位行为

背景情况:

  • 细胞膜是脂质和固醇的复杂混合物.
  • 胆固醇在膜流动性和组织中起着至关重要的作用.
  • 了解脂质-胆固醇相互作用是解读膜功能的关键.

研究的目的:

  • 为了研究二元脂质-胆固醇膜系统的相位行为.
  • 探索不同氧醇结构对膜性质的影响.
  • 阐明了所观察到的相变的基础上的分子机制.

主要方法:

  • 微角X射线散射 (SAXS) 用于确定膜结构.
  • 光显微镜可用于可视化膜领域.
  • 计算模拟用于模拟分子行为.

主要成果:

  • 两个二元脂质-胆固醇系统表现出流体-流体的共存.
  • 在部分相图中观察到闭环不混合性差距.
  • 在高温和低温时都存在单一的流体相.
  • 计算机模拟显示了温度取决于氧的方向.

结论:

  • 研究的氧醇在脂质膜中诱导独特的相位行为.
  • 氧化的分子方向是膜相变的关键因素.
  • 这些发现提供了对膜性质复杂调节的见解.