在微型CT中对固定材料的分析:它并不总是必须是聚烯泡
Jan Scherberich1, Anton G Windfelder1,2, Gabriele A Krombach1
1Department of Diagnostic and Interventional Radiology (Experimental Radiology), University Hospital Giessen, Giessen, Hesse, Germany.
PloS one
|June 14, 2023
概括
选择合适的微型CT固定材料对于高质量的成像至关重要. 这项研究比较了19种材料,发现泡,气,石和环氧树脂为传统选择提供了优秀的,具有成本效益的替代品.
科学领域:
- 材料科学 材料科学 材料科学
- 图像技术技术的成像技术
- 生物技术是生物技术.
背景情况:
- 确保微型计算机断层扫描 (micro-CT) 微妙的标本具有挑战性,冒着运动文物,过度辐射或粉碎的风险.
- 现有的固定方法往往缺乏多功能性,并可能降低样本完整性或成像质量.
研究的目的:
- 评估和比较19种不同的固定材料适用于微型CT样品的安装.
- 为了确定具有成本效益,易于获得的材料,尽量减少成像工件,并确保样本的保存.
主要方法:
- 在相同的微型CT扫描条件下 (SkyScan 1173) 测试了19种潜在的固定材料.
- 材料的评估是基于辐射密度,多孔性,可逆性和成本.
- 干固定材料以5毫米筒的形式准备,并以5.33微米的voxel尺寸扫描.
主要成果:
- 聚乙烯气,Micropor泡和聚氨泡表现出具有吸引力的低辐射密度特性 (-944至-470 HU).
- 帕拉芬颗粒和环氧树脂也被证明是合适的,放射密度分别为-640 HU和 -190 HU,通常可以通过细分来移除.
- 通常使用的塑泡可以在某些溶剂中降解,这突出了对各种材料选择的需求.
结论:
- 多种固定材料,包括泡,气,和环氧树脂,都适合微型CT,比传统方法有优势.
- 选择合适的固定材料对于获得高分辨率,无工件的微型CT图像至关重要.
- 微CT实验室应保持多样化的固定材料库存,以适应不同的样本要求和实验条件.
相关概念视频
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