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通过便微生物种移植进行微生物组改变对耐火性免疫检查点抑制剂诱导的大肠炎有效

Taylor M Halsey1, Anusha S Thomas2, Tomo Hayase3

  • 1Graduate School of Biomedical Sciences, Microbiology and Infectious Diseases, University of Texas MD Anderson Cancer Center UTHealth Houston, Houston, TX 77054, USA.

Science translational medicine
|June 14, 2023
PubMed
概括

便微生物种移植 (FMT) 在接受免疫检查点抑制剂 (ICI) 的患者中有效治疗耐火性免疫媒介性结肠炎 (IMC). FMT导致高临床缓解率和改变肠道微生物组合,表明其作为IMC的救援疗法的潜力.

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