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Single-cell Screening Method for the Selection and Recovery of Antibodies with Desired Specificities from Enriched Human Memory B Cell Populations
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CD62L表达标志着SARS-CoV-2记忆B细胞子集,具有中和表位的偏好

Taishi Onodera1, Nicolas Sax2, Takashi Sato3

  • 1Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.

Science advances
|June 14, 2023
PubMed
概括

针对SARS-CoV-2的强有力的中和抗体来源于表达较高CD62L的特定记忆B细胞 (Bmem). 这一子集表现出独特的特征,促进了对COVID-19幽默免疫的理解.

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