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Updated: Jul 26, 2025

In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction
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Published on: January 22, 2020

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活性蛋白C调节T细胞代谢和通过α-甲酸通过表观遗传FOXP3诱导

Dheerendra Gupta1, Ahmed Elwakiel1, Satish Ranjan1

  • 1Institute of Laboratory Medicine, Clinical Chemistry, and Molecular Diagnostics, University Hospital Leipzig, Leipzig University, Leipzig, Germany.

Blood advances
|June 14, 2023
PubMed
概括

活性蛋白C (aPC) 通过改变T细胞代谢来调节适应性免疫力. 这一过程减少了谷氨酸和α-谷氨酸,促进了FOXP3+调节性T细胞 (Tregs),并减少了移植对宿主疾病.

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