抗发作药物的坚持与成年患者的疾病感知之间的关联
Hyunmi Choi1, John B Wetmore2, Itzel A Camarillo3
1Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
了解与更好的抗发作药物坚持有关. 提高患者关于的知识可以提高成年患者的药物坚持.
科学领域:
- 神经学 神经学
- 心理学 心理学 心理学
背景情况:
- 影响全球数以百万计的人,需要有效的管理策略.
- 抗发作药物 (ASM) 对于控制发作至关重要,但坚持治疗可能是具有挑战性的.
- 疾病的感知,或患者如何理解和体验他们的病情,可能会影响治疗的坚持.
研究的目的:
- 研究成年患者的病感知与抗发作药物 (ASM) 坚持之间的关联.
- 确定与高ASM坚持相关的疾病感知的特定方面.
主要方法:
- 这是一项对644名成年患者的横截面调查.
- 使用莫里斯基药物坚持度表-8 (MMAS-8) 评估ASM坚持.
- 使用简要疾病感知问卷 (BIPQ) 评估疾病感知,通过后勤回归分析与坚持的关联,控制混因素.
主要成果:
- 对的更高感知理解独立地与增加的ASM坚持相关 (OR=1.17).
- 的感知更大的整体生活影响和情绪影响与较低的ASM坚持有关.
- 抑郁症,焦虑症和耻辱感调解了坚持和对生活和情绪的影响之间的反向关系.
结论:
- 更好地了解是实现高ASM坚持的关键因素.
- 旨在改善患者对的理解的干预措施可以作为一种有价值的策略,以促进药物坚持.
更多相关视频
08:23A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
Published on: November 13, 2016
07:01Electrophoretic Delivery of γ-aminobutyric Acid GABA into Epileptic Focus Prevents Seizures in Mice
Published on: May 16, 2019
相关概念视频
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Drug Therapy
Antianxiety Medications
Antiepileptic Drugs: Potassium Channel Activators
Ezogabine has gained approval as an adjunctive treatment...
Antiepileptic Drugs: Sodium Channel Blockers
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
Antiepileptic Drugs: Calcium Channel Blockers
Calcium channel blockers exert their antiepileptic effects by targeting T-type calcium channels, which are integral to transmitting nerve signals in the central nervous system. These channels allow the passage of calcium ions, which are vital for neuronal communication. By inhibiting T-type calcium channels, calcium channel blockers effectively reduce the release of neurotransmitters and...
