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用MRI向,系统或组合活检检测临床显著的前列腺癌

Kristine S Burk¹, Sachin Naik², Ronilda Lacson³

¹Center for Evidence-Based Imaging, Brigham and Women's Hospital, Boston, Massachusetts; Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts; Dana Farber Cancer Institute, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts; Quality and Safety Officer, Mass General Brigham, Boston, Massachusetts.

Journal of the American College of Radiology : JACR

|June 14, 2023

概括

结合前列腺活检可以提高前列腺癌诊断的准确性. 这种方法可以识别出比单独的向或系统活检更显著的癌症,从而提高了诊断产量.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
放射学放射学是一门学科.
在瘤学瘤学.

背景情况:

前列腺癌的诊断依赖于准确的活检方法.
多参数MRI (mpMRI) 有助于识别可疑的前列腺病变.
优化活检策略对于提高诊断准确性至关重要.

研究的目的:

为了比较MRI向,系统和联合前列腺活检的诊断准确性.
为了确定前列腺癌诊断的改进领域.
评估不同活检技术在检测前列腺癌方面的有效性.

主要方法:

追溯研究的男性高PSA和PI-RADS3-5病变在mpMRI上.
根据等级组 (GG) 分析前列腺癌诊断,使用有针对性的,系统的和联合的活检.
评估癌症升级率和接近目标活检地点的情况.

主要成果:

结合活检诊断出更多的GG ≥2前列腺癌,而不是单个方法.
与系统活检相比,向活检显示GG≥2癌症升级率更高.
在系统活检中错过的癌症往往靠近目标部位,特别是GG ≥3癌症.

结论:

结合活检在怀疑mpMRI发现的男性中更优于诊断显著的前列腺癌 (GG ≥2).
错过的癌症的接近性表明了改进向活检技术的潜力.
远距离错误可能表明MPMRI增强的机会.

关键词:

mpMRI 的时间.前列腺核磁共振 (MRI) 的前列腺.前列腺活检活检前列腺活检系统性前列腺活检有针对性的前列腺活检.

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