相关实验视频

Updated: Jul 26, 2025

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

由于心力衰竭住院治疗后,左心室喷射小部分类别的非心血管发病率和死亡率

Enrique Santas¹, Pau Llácer², Patricia Palau¹

¹Servicio de Cardiología, Hospital Clínico Universitario, Universitat de València, Instituto de Investigación Sanitaria INCLIVA, Valencia, Spain.

Revista espanola de cardiologia (English ed.)

|June 14, 2023

概括

患有心力衰竭和保存喷射分数 (HFpEF) 的患者面临非心血管死亡和再入院的风险增加. 较高的左心室喷射分数 (LVEF) 与急性心力衰竭后的非心血管发病率和死亡率更高有关.

科学领域:

心脏病学心脏病学
内部医学内部医学
公共卫生公共卫生

背景情况:

非心血管事件对心力衰竭 (HF) 患者的发病率和死亡率有显著的贡献.
这些非心血管事件的风险因左心室喷射分数 (LVEF) 状态而异.

研究的目的:

调查 LVEF 状态与非心血管疾病死亡风险和急性 HF 住院后反复性非心血管疾病再入院的相关性.

主要方法:

从一个多中心注册表中,对4595名急性HF患者的回顾性分析.
分析了LVEF作为连续变量,并分为四个类别:≤40%,41%-49%,50%-59%和≥60%.
主要终点包括随访期间的非心血管死亡率和反复的非心血管入院.

主要成果:

在平均2.2年的随访期间,记录了646例非心血管性死亡和4014例非心血管性再入院.
在多变量调整后,LVEF状态与非心血管死亡率和再录取有显著的相关性.
与LVEF≤40%的患者相比,LVEF51%-59% (HR 1.31) 和LVEF≥60% (HR 1.47) 的患者患非心血管死亡的风险更高.
患有LVEF51%-59% (IRR1.17) 和LVEF≥60% (IRR1.26) 的患者也表现出更高的非心血管性复发入院风险.

结论:

左心室喷射分数状态与急性HF入院后患者的非心血管发病率和死亡率直接相关.
患有心力衰竭和保留射出分数 (HFpEF) 的患者,特别是那些LVEF≥60%的患者,患有非心血管死亡和再入院的风险较高.

关键词:

左腹腔的眼睛的部分.心脏衰竭是因为心脏衰竭.这是心脏衰竭 (cardiaca insuficiencia).左心室喷射分数的部分.死亡率没有心血管疾病非心血管性疾病死亡率.

更多相关视频

Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs

Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs

Published on: July 12, 2022

Histological Quantification of Chronic Myocardial Infarct in Rats

Histological Quantification of Chronic Myocardial Infarct in Rats

Published on: December 11, 2016

相关概念视频

Pathophysiology of Heart Failure

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...

Heart Failure IV: Classification and Diagnostic Evaluation

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...

Heart Failure III: Clinical Manifestations

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...

Imbalances in Cardiac Output

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...

Heart Failure V: Medical Management

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...

Heart Failure I: Introduction

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...