与COVID-19患者严重程度相关的危险因素:现实世界的回顾性队列研究
Hiromichi Kawaji1, Nobuhito Kishimoto2, Naoki Muguruma3
1Department of Internal Medicine, Takamatsu Municipal Hospital, Japan.
Internal medicine (Tokyo, Japan)
|June 14, 2023
概括
老年男性更容易患上严重的COVID-19. 生物标志物,如C-反应蛋白和乳酸脱酶预测严重程度,而疫苗接种可以减少疾病的强度.
科学领域:
- 医学研究 医学研究
- 传染病 传染病 传染病
- 肺部病理学 肺部病理学
背景情况:
- 了解COVID-19严重程度的临床因素对于资源分配至关重要.
- 从2021年3月到2022年10月的四个不同的波浪中分析了COVID-19的住院患者.
研究的目的:
- 为了确定与COVID-19严重程度相关的临床因素.
- 根据疾病严重程度,评估住院和出院的需要.
主要方法:
- 546名住院COVID-19患者的回顾性分析.
- 将其分为四个波段,并比较严重程度,人口统计,胸部CT检测结果和血液检测.
- 呼吸衰竭和非呼吸衰竭组之间的统计比较.
主要成果:
- 轻度COVID-19病例在第六波之后显著增加 (超过50%).
- 胸部CT上的肺炎患病率从80%以上 (4-5波) 降至40%左右 (6-7波).
- 在呼吸衰竭和非呼吸衰竭组之间观察到年龄,性别,疫苗接种史和生物标志物的显著差异.
结论:
- 老年男性患重症COVID-19的风险更高.
- 生物标志物如C反应蛋白和乳酸脱酶在预测COVID-19严重程度方面是有效的.
- 似乎COVID-19疫苗接种与疾病严重程度的降低有关.
更多相关视频
09:36Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
2.8K
08:05Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
14.2K
相关概念视频
Factors Affecting the Risk of Infection
12.0K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.0K
COPD: Pathogenesis and Clinical Features
367
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
367
Factors Affecting Illness
4.3K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.3K
Bias in Epidemiological Studies
380
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:
380
Pneumonia I: Introduction
285
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
285
Relative Risk
238
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
238
