老年与位置性阻塞性睡眠呼吸暂停有关
Lydia Ann1, Chang-Hoon Lee2, Rachel Immen3
1Psychiatry and Behavioral Science (LA), University of California Los Angeles, CA.
概括
患有阻塞性睡眠呼吸暂停 (OSA) 的老年人更容易患有定位性睡眠暂停,这种情况可能可以通过定位治疗来治疗. 这种疗法为不能容忍CPAP的老年患者提供了替代方案.
科学领域:
- 睡眠医学 睡眠医学
- 老年病的医生 老年病的医生
- 呼吸系统医学 呼吸系统医学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 与认知问题有关,但老年患者对持续正气道压力 (CPAP) 的坚持较低.
- 定位性OSA (p-OSA) 是一种可以通过定位疗法控制的亚型,避免躺卧睡眠.
- 缺乏明确的标准来确定适合定位治疗的患者,作为CPAP的替代品或辅助.
研究的目的:
- 调查年龄较大与位置性OSA (p-OSA) 的流行之间的关系.
- 为了评估不同的诊断标准来识别p-OSA在老年人与年轻的成年人.
- 为了确定老年患者是否更有可能从定位治疗中受益.
主要方法:
- 一项横截面研究追溯分析了成年患者的多睡眠学数据.
- 定位性OSA (p-OSA) 定义为依赖卧床的呼吸事件和非卧床的呼吸暂停-呼吸暂停指数 (AHI) <5/小时.
- 逻辑回归比较了老年人 (≥65岁) 之间的p-OSA患病率和使用各种s-AHI/ns-AHI比率匹配的年轻人 (<65岁) 之间的倾向评分.
主要成果:
- 与年轻人相比,老年人表现出明显更高的卧床AHI/非卧床AHI (s-AHI/ns-AHI) 比率.
- 在倾向得分匹配后,老年患者的比例较高,具有严重的位置依赖 (例如,s-AHI/ns-AHI ≥10, ≥15, ≥20和ns-AHI <5/小时).
- 几率比率表明,在老年人中,严重的p-OSA的可能性是2.24至2.52倍.
结论:
- 患有OSA的老年患者更有可能患有严重的定位性OSA.
- 定位疗法为老年OSA患者提供了可行的替代或辅助治疗,特别是那些认知障碍或CPAP不耐受的人.
- 这项研究支持考虑OSA的老年人定位治疗,优化治疗坚持和结果.
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