轻微的非特异性ST段和T波异常与冠状动脉化之间的关系中的性别差异
1Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, 04514, Republic of Korea; Department of Clinical Research Design & Evaluation, SAIHST, Sungkyunkwan University, Seoul, 06355, Republic of Korea.
轻微的心电图异常与男性的冠状动脉化有关,但与女性无关. 这表明非特异性ST段和T波异常是男性冠状动脉疾病的性别特异性风险因素.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 公共卫生 公共卫生
背景情况:
- 非特异性ST段和T波异常 (NSSTTA) 与不良心血管结果有关.
- NSSTTA与亚临床动脉样硬化之间的关联尚未得到充分证实.
- 电心电图 (ECG) 异常可能表明潜在的冠状动脉疾病.
研究的目的:
- 研究包括NSSTTA在内的心电图异常与冠状动脉化 (CAC) 之间的关联.
- 为了确定NSSTTA是否与亚临床动脉样硬化有关.
- 探索潜在的性别差异在ECG异常和CAC之间的关联.
主要方法:
- 对136,461名韩国参与者的横截面研究.
- 脑电图和计算机断层扫描用于冠状动脉分数 (CACS) 测量.
- 使用明尼苏达州代码和多项物流回归的自动化心电图分析.
主要成果:
- 在男性中,NSSTTA和主要心电图异常都与所有CACS水平有关.
- 在女性中,只有主要的心电图异常与CACS相关 (101-400).
- 在女性中,NSSTTA与任何CACS水平无关.
结论:
- NSSTTA和主要的ECG异常与男性的CAC有关.
- 在女性中,NSSTTA与CAC无关.
- NSSTTA可能是男性冠状动脉疾病的性别特异性风险因素.
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