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Updated: Jul 26, 2025

Detection of Homologous Recombination Intermediates via Proximity Ligation and Quantitative PCR in Saccharomyces cerevisiae
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Published on: September 11, 2022

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突破诱导的复制编排了切割依赖的模板切换

Tianpeng Zhang1, Yashpal Rawal2, Haoyang Jiang1

  • 1Department of Cancer Biology, Penn Center for Genome Integrity, Basser Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Nature
|June 14, 2023
PubMed
概括

破裂诱导的端粒合成 (BITS) 使用最小的复制体进行DNA修复. 在此过程中,SNM1A核酶指导无处不在的PCNA促进切除和病变绕道.

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