轻微的COVID-19对精液质量没有不利影响
Philippos Edimiris1, Cornelius Doehmen2,3, Lisa Müller4
1Department of OB/GYN and REI (UniKiD), Medical Center, University of Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany. Philippos.edimiris@med.uni-duesseldorf.de.
Basic and clinical andrology
|June 14, 2023
概括
2019年轻型冠状病毒病 (COVID-19) 似乎不会对男性生育能力产生负面影响. 在对患有轻度COVID-19的男性进行的一项研究中,精液参数没有受到影响,精液中没有检测到SARS-CoV-2.
科学领域:
- 生殖健康 生殖健康
- 病毒学 病毒学
- 传染性疾病 传染性疾病
背景情况:
- COVID-19对男性生育能力的影响尚未得到充分证实,现有的研究结果相互矛盾.
- 以前的研究往往受到小样本大小和多样化的患者群体的影响.
- 需要更深入地了解COVID-19对男性生殖健康的影响.
研究的目的:
- 为了研究轻度的COVID-19对男性生育能力的影响.
- 在COVID-19的急性阶段分析男性的精液参数.
- 为了确定射精中SARS-CoV-2的存在.
主要方法:
- 未来病例控制研究涉及37名受试者 (25名患有轻度COVID-19,12名对照).
- 精液参数的分析,包括精子数,运动性和形态学.
- 严重急性呼吸道综合征冠状病毒2型 (SARS-CoV-2) 定量聚合酶连锁反应 (qPCR) 和感染性测定.
主要成果:
- 在患有轻度COVID-19的男性和对照组之间没有观察到精液参数的显著差异.
- 连续检查显示,4日,18日和82日症状出现后的精液参数没有显著变化.
- 在任何分析的射精中都没有检测到SARS-CoV-2RNA或传染性病毒颗粒.
结论:
- 轻微的COVID-19似乎对男性精液参数没有不利影响.
- 这些发现表明,轻微的SARS-CoV-2感染不会影响男性的生育能力.
- 进一步的研究可能会探索严重的COVID-19对男性生育能力的长期影响或影响.
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