在栓塞治疗中控制栓塞剂的注射速度
Dongcheng Ren1,2,3, Bo Zhou4,5, Jiasheng Li1,2,3
1Academy for Engineering and Technology, Fudan University, 220 Handan Rd., Shanghai, China.
Biomedical engineering online
|June 14, 2023
概括
本研究介绍了栓塞注射的流量控制模型,使用局部动脉压来指导程序. 这项创新旨在预防子宫外栓塞并减少干预栓塞期间的辐射暴露.
科学领域:
- 干预性放射学 干预性放射学
- 生物医学工程 生物医学工程
- 流体动力学 流体动力学
背景情况:
- 栓塞对于治疗瘤,高功能器官和出血至关重要.
- 目前的栓塞技术在很大程度上依赖于医生的经验,并涉及辐射暴露.
- 风险包括由于不精确的栓塞剂输送而导致的宫外栓塞.
研究的目的:
- 开发基于局部动脉压的栓塞注射流量控制模型.
- 在栓塞过程中模拟和分析血液动力学变化.
- 评估自动化栓塞注射系统的潜力.
主要方法:
- 建立了用于栓塞注射的流量控制曲线模型.
- 简化了终端容器网络作为一个多孔介质.
- 模拟的血液动力学变化和用于体外实验的海绵模型.
主要成果:
- 当地动脉压与临界注射速度和栓塞程度相关.
- 该模型有效地模拟了毛细血管网络中的栓塞剂行为.
- 证明了注射速度,压力和栓塞之间的关系.
结论:
- 流量控制曲线模型可以减少子宫外栓塞风险和手术时间.
- 这个模型对自动化栓塞注射系统有希望.
- 临床应用在减少辐射暴露和提高栓塞成功率方面提供了显著的好处.
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