二氧化对发生在牙科椅子单元中的致病性水性微生物的影响
Theresa Isabella Maria Krüger1, Susann Herzog1, Alexander Mellmann1
1Institute of Hygiene, University Hospital Münster, Robert Koch-Straße 41, 48149 Münster, Germany.
Microorganisms
|June 15, 2023
概括
二氧化 (ClO2) 有效消毒牙科单位的水道,但细菌耐受性因环境因素和微生物类型而异. 较高的度和较短的暴露时间改善了细菌的减少.
科学领域:
- 环境微生物学环境微生物学
- 传染病控制中的传染病控制
- 水处理技术水处理技术.
背景情况:
- 牙科单位的水管 (DUWL) 容易受到细菌污染,因此需要定期的消毒协议.
- 在DUWL中的微生物生物膜对患者和牙科专业人员构成重大感染风险.
- 二氧化 (ClO2) 是一种用于水处理的强效消毒剂,但其在DUWL中的有效性需要详细的研究.
研究的目的:
- 评估二氧化 (ClO2) 消毒对牙科单位水道中的关键水源病原体的短期疗效.
- 调查环境背景 (盐水,酸盐缓冲盐水,自来水) 对ClO2消毒有效性的影响.
- 评估细菌密度和微生物特征 (格拉姆阳性与格拉姆阴性) 对ClO2耐受性的影响.
主要方法:
- 特定的细菌物种 (Legionella pneumophila,L. anisa,Pseudomonas aeruginosa,Escherichia coli,Staphylococcus aureus) 暴露在不同度的二氧化 (0.4 mg/L和4.6 mg/L) 中.
- 在不同的水性矩阵中测试消毒功效:自来水,盐水和酸盐缓冲盐水.
- 细菌还原动力学的分析,包括最初的快速无活化和随后的较慢的还原阶段.
主要成果:
- 环境背景显著影响了ClO2的有效性;盐水和酸缓冲盐水显示出比自来水更大的细菌减少.
- 格拉姆阳性细菌对ClO2的耐受性高于格拉姆阴性细菌. 适应自来水的细菌比培养细胞更强壮.
- 较高的细菌密度抵抗了消毒,但增加的ClO2度 (4.6 mg/L) 提高了无活化率. 观察到一个双相无活化模式.
结论:
- 二氧化在DUWL中对目标微生物具有很高的消毒效率,其有效性受背景溶液和细菌特征的影响.
- 细菌对ClO2的耐受性是多因素的,涉及环境适应,固有的微生物特性和细菌密度,而不仅仅是消毒剂度.
- 对DUWL的优化消毒策略应考虑这些变量,以确保有效的微生物控制和患者安全.
关键词:
军团菌 (Legionella) 是一种传染病.伪omonas空气菌 伪omonas空气菌黄金葡萄球菌黄金葡萄球菌二氧化二氧化的使用方法牙科单位 水线 牙科单位 水线消毒 消毒 消毒 消毒感染控制的方法更多相关视频
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