野生巨型真菌的营养价值和抗氧化,抗微生物和细胞毒性活性
Lina Rocío Dávila Giraldo1,2, Claudia Cristina Pérez Jaramillo1, Jonh Jairo Méndez Arteaga1
1Grupo de Investigación en Productos Naturales, GIPRONUT, Universidad del Tolima, Ibagué 730006, Colombia.
Microorganisms
|June 15, 2023
概括
野生哥伦比亚巨型真菌具有重要的营养价值,特别是来自Pleurotus和Lentinus物种的蛋白质含量. 提取物还显示出有前途的抗氧化,抗微生物和细胞毒性活动,突出显示了它们的治疗潜力.
科学领域:
- 菌类学 菌类学是指菌类学.
- 自然产品 化学 化学
- 药理学是指药理学,即药理学是指药理学.
背景情况:
- 大菌因其营养和药用特性而闻名.
- 野生是新生物活性化合物的尚未开发的资源.
- 哥伦比亚的生物多样性提供了丰富的未开发的宏观真菌物种来源.
研究的目的:
- 为了评估来自哥伦比亚Ibague-Tolima的9种野生巨的营养成分.
- 评估宏真菌提取物的抗氧化,抗微生物和细胞毒性活动.
- 确定具有食品和制药应用高潜力的特定物种.
主要方法:
- 宏菌生物质的营养分析.
- 制备乙醇:水 (70:30) 提取物从野生基底植物.
- 使用激素稳定试验 (IC50) 评估抗氧化活性.
- 对抗细菌和真菌病原体的抗微生物疗效的评估.
- 使用单独的白细胞进行细胞毒性测试.
主要成果:
- *Pleurotus*和*Lentinus*属的蛋白质含量最高 (分别为18.4%和18.5%).
- *Phellinus gilvus*和*Ganoderma australe*提取物显示出强大的抗氧化活性,IC50值较低.
- *Trametes coccinea*, *Pleurotus floridanus* 和 *Ganoderma australe* 显示出对测试的细菌具有显著的抗菌活性.
- 所有九种提取物都是有效的抗真菌药物,可以对抗*Rhizopus oryzae*,*Penicillium* sp.和*Aspergillus niger*.
- 在9种提取物中,有7种在单独的白细胞中保持了50%以上的细胞活力.
结论:
- 来自哥伦比亚的野生宏观真菌具有宝贵的营养特征,特别是高蛋白质含量.
- 评估的宏真菌提取物具有显著的抗氧化剂和广泛的抗微生物特性.
- 一些物种,包括Pleurotus,Lentinus,Phellinus gilvus和Ganoderma australe,显示出相当大的发展潜力,作为功能性食物或治疗剂.
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