乳酸细菌的益生菌性质和抗氧化活性在体外
Despina Vougiouklaki1, Theofania Tsironi2, Andreas G Tsantes3
1Department of Food Science and Technology, Faculty of Food Sciences, University of West Attica, 12461 Egaleo, Greece.
Microorganisms
|June 15, 2023
概括
测试了四种乳酸细菌 (LAB) 菌株的肠道生存,抗生素耐药性和抗氧化特性. 乳植物菌植物体表现出优异的肠道存活率,而L. brevis和L. gasseri表现出显著的抗氧化活性.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 胃肠病学 胃肠病学
背景情况:
- 乳酸细菌 (LAB) 由于其益生菌性质而得到广泛认可.
- 了解人类肠道中的LAB生存和功能对于其应用至关重要.
研究的目的:
- 评估四种特定的LAB物种在模拟的胃肠道条件下的生存情况.
- 评估这些LAB菌株的抗生素耐药性概况和细菌素基因存在.
- 为了研究LAB代谢物的抗氧化活性.
主要方法:
- 实验室菌株被暴露在模拟的胃汁中,并测试了它们的生存率.
- 使用标准敏感性测试来确定抗生素耐药性.
- 鉴定了细菌素基因 (Pediocin PA,PlnEF,Brevicin 174A,PlnA).这些基因被发现.
- 使用DPPH激素清除和抑制DNA分裂来评估抗氧化活性.
主要成果:
- 这四种LAB菌株都对模拟的胃状况有很高的耐受性.
- 在人类肠道中,Lactiplantibacillus plantarum表现出最高的存活率.
- 没有任何菌株对测试的抗生素表现出耐药性.
- 在一些菌株中检测到Pediocin PA和PlnEF基因;Brevicin 174A和PlnA没有.
- L. brevis和L. gasseri表现出强大的抗氧化活性.
结论:
- 选择的LAB菌株对肠道生存和潜在的益生菌应用具有有利的特征.
- L. plantarum是肠道健康的有希望的候选人,而L. brevis和L. gasseri提供显著的抗氧化剂益处.
- 这些发现支持在食品工业中使用这些LAB来开发功能性食品.
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