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动物性出血性疾病病毒:当前知识和新兴前景

Luis Jiménez-Cabello¹, Sergio Utrilla-Trigo¹, Gema Lorenzo¹

¹Centro de Investigación en Sanidad Animal (CISA-INIA/CSIC), Valdeolmos, 28130 Madrid, Spain.

|June 15, 2023

概括

动物性出血性疾病 (EHD) 是全球反动物日益严重的威胁. 本综述涵盖了EHDV的分布,毒性,动物模型和这种重大病毒性疾病的潜在治疗方法.

科学领域:

兽医病毒学兽医病毒学
传染病流行病学传染病流行病学
动物健康与福利动物健康与福利

背景情况:

动物性出血性疾病 (Epizootic Hemorrhagic Disease,简称EHD) 是一种严重的病毒性疾病,影响反动物,造成大量的经济和福利损失.
动物性出血性疾病病毒 (EHDV),一种Orbivirus,在多个大陆对牲畜和野生动物的广泛爆发负责.
最近在地中海和欧盟爆发的EHDV疫情凸显了其不断扩大的威胁,气候变化驱动的载体分布加剧了这种威胁.

研究的目的:

提供关于EHDV的当前知识的全面概述.
检查EHDV.的分布和毒力变化的情况.
讨论动物模型和EHDV.潜在的控制策略.

主要方法:

对EHDV.现有研究的文献综述.
对EHDV爆发和分布的流行病学数据的分析.
对动物模型和EHDV治疗干预措施的研究进行审查.

主要成果:

在频率和地理范围上,EHDV疫情正在增加,特别是在地中海盆地和欧盟.
全球气候变化正在促进有能力的Culicoides中载体的扩张.
已使用多种动物模型来研究EHDV病原和宿主反应.

结论:

在全球范围内,EHDV对全球畜牧业和野生反动物种群构成严重和不断扩大的风险.
了解EHDV的分布,毒性和宿主-病原体相互作用对于有效的疾病管理至关重要.
对新型治疗方法和控制措施的进一步研究是必要的,以减轻EHDV的影响.

关键词:

这是一个 EHDVV.这里是牛群.流行病学流行病学疫苗,疫苗,疫苗的使用情况.白尾鹿是一种白尾鹿.

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