听力损伤在患有白发症的患者
Safoura Shakoei1, Elahe Mohammadnia2, Babak Saedi3
1Department of Dermatology, Imam Khomeini Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Indian journal of dermatology, venereology and leprology
|June 15, 2023
概括
与健康个体相比,患有大发性脱发症的患者表现出较高的听力损失患病率. 这表明自身免疫性疾病和听觉功能之间存在潜在的联系,可能是由于涉及黑色素细胞的共享机制.
科学领域:
- 皮肤病学 皮肤病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 免疫学 免疫学 免疫学
背景情况:
- 大发脱发是一种针对毛囊的自身免疫性疾病.
- 毛囊黑色素细胞可能与自身免疫过程有关.
- 大发性脱毛和神经感官听力损失之间的潜在联系,类似于白风.
研究的目的:
- 在被诊断为有形脱发症的患者中调查潜在的听力障碍.
- 为了比较白发病患者与健康对照者的听觉功能.
主要方法:
- 横截面研究涉及42名脱发区患者和42名健康对照.
- 使用耳声发射,纯音声听力测量和前庭唤起肌体潜能测试进行听力评估.
- 语音识别值和语音歧视得分的分析.
主要成果:
- 脱发症患者的正常耳声排放率明显较低 (59.5%与100%相比).
- 较高的语音识别值和较差的语音歧视得分在白发症群体中被观察到.
- 在8000 Hz时注意到听力值增加;在500和1000 Hz时没有显著差异.
- 在14% (单边) 和4.8% (双边) 的脱发区患者中,没有引起静脉质潜在反应.
结论:
- 听力损失在患有白发症的个体中更为普遍.
- 在白发性脱发中,对毛囊黑色素细胞的自身免疫性攻击可能会影响内耳听力功能.
- 没有发现脱发区持续时间/严重程度和听力损失程度之间有显著的相关性.
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