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在中国实现并改善稳定的COPD管理:多中心,前性,观察性研究 (REAL) 的结果

Ting Yang^1,2, Baiqiang Cai³, Bin Cao^1,2

¹Department of Pulmonary and Critical Care Medicine, National Clinical Research Centre for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China.

Therapeutic advances in respiratory disease

|June 15, 2023

概括

在中国,慢性阻塞性肺病 (COPD) 的管理不充分,恶化率高,治疗坚持率低. 这项研究强调,迫切需要在全国范围内改进COPD护理策略,以提高患者的治疗结果.

科学领域:

肺病学和呼吸系统医学
慢性疾病管理中的现实世界的证据

背景情况:

中国的慢性阻塞性肺病 (COPD) 管理面临重大挑战,包括诊断不足和治疗不足,阻碍了最佳的患者护理.
现有的关于中国现实世界COPD管理的数据有限,需要进行全面的调查.

研究的目的:

评估COPD管理,患者的治疗结果,治疗模式,坚持和真实中国人口的疾病知识.
确定全国性COPD护理的关键障碍和改善领域.

主要方法:

这是一项为期52周的多中心前性观察性研究,涉及4978名40岁及以上的诊断为COPD的门诊患者.
数据收集是在中国6个地理区域的50家医院的常规临床实践中进行的.
评估了恶化率,症状负担 (COPD评估测试,COPD问卷),治疗处方和药物坚持.

主要成果:

观察到中度至非常严重的空气流限制率高 (90%) 和显著的恶化负担 (总体为0.56,每年严重的恶化为0.31).
尽管接受了治疗,但在随访时,42-55%的患者出现了持续的呼吸道症状.
长效吸入器的治疗坚持率很低 (59.0%),高风险患者 (GOLD C和D组) 的治疗坚持率低于最佳水平.

结论:

患有COPD的中国门诊患者经历了严重恶化和持续症状的大量负担.
目前的治疗坚持和指导方针实施不足,这凸显了中国全境加强慢性肺炎管理策略的迫切需要.

关键词:

慢性慢性肺炎是一种慢性慢性肺炎,COPD是一种慢性肺炎.中国中国中国中国.疾病负担疾病负担观察性研究是一种观察性研究.门诊患者门诊患者

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