维生素D的低维生素和COVID-19的严重形式之间的关联
M Manojlovic1, B Ilincic, D T Naglic
1Faculty of Medicine Novi Sad, University of Novi Sad, Novi Sad, Serbia. mia.manojlovic@mf.uns.ac.rs.
European review for medical and pharmacological sciences
|June 15, 2023
概括
严重的维生素D缺乏与更糟糕的COVID-19结果有关. 维生素D水平较低的患者在医院住院时间较长,死亡率增加,这表明在疾病严重程度方面发挥了重要作用.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 维生素D缺乏 (维生素D缺乏症) 是增加感染易感性和严重COVID-19的潜在危险因素.
- 了解维生素D状态和COVID-19严重程度之间的关系对于患者管理至关重要.
研究的目的:
- 调查血清25-基维生素D (25(OH) D) 水平与COVID-19的严重程度之间的关联.
- 探索维生素D状况与其他心脏代谢风险因素在COVID-19患者中的作用.
主要方法:
- 2021年进行了一项涉及成年COVID-19患者的横截面研究.
- 收集的数据包括人体测量测量,并发病,住院,住院时间,呼吸辅助,结果和血清25...OH) D水平.
主要成果:
- 在74名参与者中,44.6%有严重的维生素D缺乏 (<30nmol/l).
- 患有严重COVID-19的患者 (需要半ICU或ICU护理) 与较不严重的病例 (32.9 nmol/l) 相比,血清25(OH) D水平 (20.5 nmol/l) 显著降低.
- 严重的维生素D缺乏与年龄较大,高血压流行,需要机械通风和较高的死亡率 (24.2%) 相关.
结论:
- 严重的维生素D缺乏是COVID-19严重性的一个重要因素.
- 缺陷可能会加剧其他心脏代谢风险因素对COVID-19结果的影响.
- 保持足够的维生素D水平可能对减轻COVID-19的严重程度很重要.
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