脑小脑静音综合征:风险评估,预防和治疗
Jonathan Kjær Grønbæk1,2, Ditte Boeg Thomsen3, Karin Persson4,5
1Department of Neurosurgery, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark. jonathan.kjaer.groenbaek@regionh.dk.
Advances and technical standards in neurosurgery
|June 15, 2023
概括
儿童大脑默综合征 (CMS),后手术的并发症,仍然难以预防或治疗. 早期的言语和语言治疗可以改善长期的言语和神经认知结果.
科学领域:
- 儿科神经外科 儿科神经外科
- 神经学 神经学
- 语音语言病理学 语音语言病理学
背景情况:
- 大脑默综合征 (CMS) 是儿童后瘤手术后的一种已知的并发症.
- 尽管对风险因素和治疗方法进行了研究,但CMS的发病率并未下降,预防仍然具有挑战性.
- 目前的症状治疗缺乏随机对照试验的强有力的证据,与自然恢复相比,它们的疗效尚不清楚.
研究的目的:
- 审查当前对儿科患者大脑静音综合征 (CMS) 的理解.
- 突出预防和治疗手术后CMS的持续挑战.
- 强调研究早期语音和语言治疗的必要性,以改善长期结果.
主要方法:
- 对关于大脑静音综合征的现有文献的综述.
- 分析报告的风险因素,病因方面和治疗策略.
- 讨论CMS对言语,语言和神经认知功能的影响.
主要成果:
- 尽管确定了风险因素,但CMS的发病率仍然没有变化.
- 药理治疗的证据有限,其有效性尚未得到充分证实.
- 大多数儿童在几个月内恢复发言能力,但许多儿童经历了持续的言语和语言缺陷,并存在神经认知后续的风险.
结论:
- 目前,CMS缺乏有效的预防和治疗策略.
- 长期的言语和语言障碍是CMS的常见后果.
- 对早期和密集的语音和语言治疗进行进一步的研究是有必要的,以改善功能恢复.
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