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Updated: Jul 26, 2025

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
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甲型流感诱发的囊性纤维化,膜传导性调节器功能障碍增加了对Streptococcus pneumoniae的易感性

Erin Y Earnhardt1, Jennifer L Tipper1, Adonis D'Mello2

  • 1Department of Anesthesiology and Perioperative Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.

JCI insight
|June 15, 2023
PubMed
概括

流感A病毒感染通过降低囊性纤维化跨膜导电性调节器 (CFTR) 功能来损害呼吸道防御,增加对二次细菌性肺炎的易感性. 这突显了肺上皮在病毒感染期间宿主防御中的关键作用.

关键词:
细菌感染 细菌感染传染性疾病传染性疾病.流感是一次流感.离子通道的离子通道病毒学 病毒学

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