针及其恢复和维持免疫平衡的能力
1Department of Integrated Traditional Chinese and Western Medicine, First Affiliated Hospital of Harbin Medical University, Harbin 150001, P. R. China.
QJM : monthly journal of the Association of Physicians
|June 15, 2023
概括
针可以通过双向调节免疫系统来恢复免疫平衡. 这种方法为癌症和自身免疫性疾病等与免疫相关的疾病提供了一种新的治疗策略.
科学领域:
- 免疫学 免疫学 免疫学
- 综合医学是一个整体的医学.
背景情况:
- 免疫平衡对于宿主防御和预防自身免疫性至关重要.
- 免疫平衡的破坏与癌症和自身免疫性疾病等疾病有关.
- 目前的治疗方法提供单向免疫调节,冒着不良影响的风险.
研究的目的:
- 系统地审查针的双向免疫调节机制.
- 探索针在恢复免疫恒温的潜力,以获得治疗效益.
- 建议针作为一种免疫正常化的方法.
主要方法:
- 关于针和免疫功能研究的综合文献综述.
- 对疗效应的拟议分子和细胞机制的分析.
- 关于针对免疫细胞群和细胞因子平衡的影响的综合证据.
主要成果:
- 针证明了双向免疫调节,在免疫抑制状态 (例如癌症) 中增强免疫力,并在自身免疫条件下抑制免疫力.
- 关键的机制包括增强自然杀手 (NK) 和CD8+T细胞功能.
- 针有助于恢复T辅助细胞子集 (Th1/Th2,Th17/Treg) 和巨分化 (M1/M2) 的平衡.
结论:
- 针可以促进免疫正常化,为免疫功能障碍提供一种潜在的治疗方法.
- 针的双向调节效应为治疗复杂的免疫相关疾病提供了一个有希望的策略.
- 对针对免疫系统调节的治疗潜力的进一步研究是有必要的.
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